| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| mutM | radA | sync_0561 | sync_2596 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.406 |
| mutM | sync_1439 | sync_0561 | sync_1439 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.671 |
| nnrD | sync_1439 | sync_0760 | sync_1439 | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.547 |
| radA | mutM | sync_2596 | sync_0561 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.406 |
| radA | sync_1439 | sync_2596 | sync_1439 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.410 |
| sync_1437 | sync_1438 | sync_1437 | sync_1438 | Predicted exonuclease involved in mRNA processing. | Possible ATP-dependent DNA ligase; Identified by match to protein family HMM PF01068; match to protein family HMM PF04679. | 0.994 |
| sync_1437 | sync_1439 | sync_1437 | sync_1439 | Predicted exonuclease involved in mRNA processing. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.886 |
| sync_1437 | sync_1732 | sync_1437 | sync_1732 | Predicted exonuclease involved in mRNA processing. | Serine/threonine specific protein phosphatase; Identified by match to protein family HMM PF00149. | 0.800 |
| sync_1438 | sync_1437 | sync_1438 | sync_1437 | Possible ATP-dependent DNA ligase; Identified by match to protein family HMM PF01068; match to protein family HMM PF04679. | Predicted exonuclease involved in mRNA processing. | 0.994 |
| sync_1438 | sync_1439 | sync_1438 | sync_1439 | Possible ATP-dependent DNA ligase; Identified by match to protein family HMM PF01068; match to protein family HMM PF04679. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.885 |
| sync_1438 | sync_1732 | sync_1438 | sync_1732 | Possible ATP-dependent DNA ligase; Identified by match to protein family HMM PF01068; match to protein family HMM PF04679. | Serine/threonine specific protein phosphatase; Identified by match to protein family HMM PF00149. | 0.813 |
| sync_1439 | mutM | sync_1439 | sync_0561 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.671 |
| sync_1439 | nnrD | sync_1439 | sync_0760 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.547 |
| sync_1439 | radA | sync_1439 | sync_2596 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.410 |
| sync_1439 | sync_1437 | sync_1439 | sync_1437 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Predicted exonuclease involved in mRNA processing. | 0.886 |
| sync_1439 | sync_1438 | sync_1439 | sync_1438 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Possible ATP-dependent DNA ligase; Identified by match to protein family HMM PF01068; match to protein family HMM PF04679. | 0.885 |
| sync_1439 | sync_1440 | sync_1439 | sync_1440 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Conserved hypothetical protein; Identified by similarity to GB:CAE21207.1. | 0.548 |
| sync_1439 | sync_1441 | sync_1439 | sync_1441 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Conserved hypothetical protein; Identified by similarity to GB:CAE19476.1. | 0.548 |
| sync_1439 | sync_1732 | sync_1439 | sync_1732 | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | Serine/threonine specific protein phosphatase; Identified by match to protein family HMM PF00149. | 0.817 |
| sync_1440 | sync_1439 | sync_1440 | sync_1439 | Conserved hypothetical protein; Identified by similarity to GB:CAE21207.1. | ATP-dependent helicase, DEAD/DEAH box family protein; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. | 0.548 |