murI protein (Synechococcus sp. CC9311) - STRING interaction network

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Score

murI

Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (263 aa)

Predicted Functional Partners:

murD

0.975

rdgB

0.915

sync_0737

0.900

purQ

0.900

amiC

0.837

glnA

0.836

sync_0105

0.830

sync_1548

0.812

sync_1253

0.808

sync_0455

0.800

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
amiC	murI	sync_1549	sync_1550	Cell wall hydrolase/autolysin; Identified by match to protein family HMM PF01520.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.837
amiC	sync_1548	sync_1549	sync_1548	Cell wall hydrolase/autolysin; Identified by match to protein family HMM PF01520.	Possible nitrilase; Identified by match to protein family HMM PF00795.	0.814
glnA	murI	sync_1569	sync_1550	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.836
glnA	purQ	sync_1569	sync_1701	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]	0.906
glnA	sync_0105	sync_1569	sync_0105	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	Putative glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.	0.928
glnA	sync_0455	sync_1569	sync_0455	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family.	0.904
glnA	sync_1253	sync_1569	sync_1253	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.	0.941
murD	murI	sync_2260	sync_1550	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.975
murD	purQ	sync_2260	sync_1701	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]	0.900
murD	sync_0737	sync_2260	sync_0737	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Uncharacterized conserved protein; Identified by match to protein family HMM PF07755.	0.900
murI	amiC	sync_1550	sync_1549	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Cell wall hydrolase/autolysin; Identified by match to protein family HMM PF01520.	0.837
murI	glnA	sync_1550	sync_1569	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Glutamine synthetase, type I; Identified by similarity to SP:P05457; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653.	0.836
murI	murD	sync_1550	sync_2260	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	0.975
murI	purQ	sync_1550	sync_1701	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]	0.900
murI	rdgB	sync_1550	sync_0272	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.915
murI	sync_0105	sync_1550	sync_0105	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Putative glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.	0.830
murI	sync_0455	sync_1550	sync_0455	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family.	0.800
murI	sync_0737	sync_1550	sync_0737	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Uncharacterized conserved protein; Identified by match to protein family HMM PF07755.	0.900
murI	sync_1253	sync_1550	sync_1253	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.	0.808
murI	sync_1548	sync_1550	sync_1548	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	Possible nitrilase; Identified by match to protein family HMM PF00795.	0.812