| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | guaA | sync_1204 | sync_0047 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.768 |
| carB | pyrB | sync_1204 | sync_0343 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | sync_1204 | sync_1922 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.719 |
| carB | pyrD | sync_1204 | sync_2721 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.955 |
| carB | pyrE-2 | sync_1204 | sync_0364 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | PyrF/pyrE bifunctional enzyme; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
| carB | sync_2013 | sync_1204 | sync_2013 | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | Dihydroorotase, putative. | 0.943 |
| guaA | carB | sync_0047 | sync_1204 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.768 |
| guaA | pyrB | sync_0047 | sync_0343 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.759 |
| guaA | pyrC | sync_0047 | sync_1922 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.537 |
| guaA | pyrD | sync_0047 | sync_2721 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.758 |
| guaA | pyrE-2 | sync_0047 | sync_0364 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | PyrF/pyrE bifunctional enzyme; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.809 |
| guaA | sync_2013 | sync_0047 | sync_2013 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Dihydroorotase, putative. | 0.485 |
| pyrB | carB | sync_0343 | sync_1204 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.999 |
| pyrB | guaA | sync_0343 | sync_0047 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.759 |
| pyrB | pyrC | sync_0343 | sync_1922 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.976 |
| pyrB | pyrD | sync_0343 | sync_2721 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.961 |
| pyrB | pyrE-2 | sync_0343 | sync_0364 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | PyrF/pyrE bifunctional enzyme; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.999 |
| pyrB | sync_2013 | sync_0343 | sync_2013 | Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase, putative. | 0.999 |
| pyrC | carB | sync_1922 | sync_1204 | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. | 0.719 |
| pyrC | guaA | sync_1922 | sync_0047 | Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.537 |