folE protein (Synechococcus sp. CC9311) - STRING interaction network

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Score

folE

GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. (247 aa)

Predicted Functional Partners:

folK

0.979

folP

0.977

folB

0.970

ribAB

0.961

sync_1898

0.943

sync_2556

0.943

moaA

0.915

ndk

0.833

bdh

0.803

sync_1265

0.800

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bdh	folE	sync_1987	sync_1986	Short-chain dehydrogenase/reductase family enzyme; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	0.803
folB	folE	sync_1877	sync_1986	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	0.970
folB	folK	sync_1877	sync_0249	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	0.996
folB	folP	sync_1877	sync_1211	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.995
folB	ribAB	sync_1877	sync_1383	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.611
folE	bdh	sync_1986	sync_1987	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Short-chain dehydrogenase/reductase family enzyme; Identified by match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.803
folE	folB	sync_1986	sync_1877	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	0.970
folE	folK	sync_1986	sync_0249	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	0.979
folE	folP	sync_1986	sync_1211	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.977
folE	moaA	sync_1986	sync_2885	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.	0.915
folE	ndk	sync_1986	sync_2741	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.833
folE	ribAB	sync_1986	sync_1383	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.961
folE	sync_1265	sync_1986	sync_1265	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Ribonucleotide reductase (Class II); Identified by match to protein family HMM TIGR02505.	0.800
folE	sync_1898	sync_1986	sync_1898	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	Conserved hypothetical protein.	0.943
folE	sync_2556	sync_1986	sync_2556	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	6-pyruvoyl-tetrahydropterin synthase homolog; Identified by match to protein family HMM PF01242.	0.943
folK	folB	sync_0249	sync_1877	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	0.996
folK	folE	sync_0249	sync_1986	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.	0.979
folK	folP	sync_0249	sync_1211	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.998
folK	ribAB	sync_0249	sync_1383	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.	Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.660
folP	folB	sync_1211	sync_1877	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	Dihydroneopterin aldolase; Identified by match to protein family HMM PF02152; match to protein family HMM TIGR00526.	0.995