| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cbiG/cobJ | cobC | sync_0391 | sync_2012 | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | 0.561 |
| cbiG/cobJ | cobQ | sync_0391 | sync_0893 | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.998 |
| cobC | cbiG/cobJ | sync_2012 | sync_0391 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.561 |
| cobC | cobQ | sync_2012 | sync_0893 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.413 |
| cobC | ftsI | sync_2012 | sync_2009 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Cell division protein FtsI/penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717. | 0.540 |
| cobC | glyA | sync_2012 | sync_0300 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.654 |
| cobC | pyk | sync_2012 | sync_1415 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.493 |
| cobC | sync_0045 | sync_2012 | sync_0045 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Soluble hydrogenase, tritium exchange subunit, putative; Identified by similarity to SP:P14776; match to protein family HMM PF00266. | 0.511 |
| cobC | sync_0387 | sync_2012 | sync_0387 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Ferredoxin-dependent glutamate synthase, Fd-GOGAT; Identified by match to protein family HMM PF00310; match to protein family HMM PF00478; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.457 |
| cobC | sync_2011 | sync_2012 | sync_2011 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | CAAX amino terminal protease family protein; Identified by match to protein family HMM PF02517. | 0.608 |
| cobC | sync_2013 | sync_2012 | sync_2013 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Dihydroorotase, putative. | 0.811 |
| cobC | tal | sync_2012 | sync_2008 | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. | 0.428 |
| cobQ | cbiG/cobJ | sync_0893 | sync_0391 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.998 |
| cobQ | cobC | sync_0893 | sync_2012 | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | 0.413 |
| ftsI | cobC | sync_2009 | sync_2012 | Cell division protein FtsI/penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717. | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | 0.540 |
| ftsI | sync_2011 | sync_2009 | sync_2011 | Cell division protein FtsI/penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717. | CAAX amino terminal protease family protein; Identified by match to protein family HMM PF02517. | 0.623 |
| ftsI | sync_2013 | sync_2009 | sync_2013 | Cell division protein FtsI/penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717. | Dihydroorotase, putative. | 0.427 |
| ftsI | tal | sync_2009 | sync_2008 | Cell division protein FtsI/penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. | 0.678 |
| glyA | cobC | sync_0300 | sync_2012 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. | 0.654 |
| glyA | pyk | sync_0300 | sync_1415 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.678 |