cobC protein (Synechococcus sp. CC9311) - STRING interaction network

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Score

cobC

Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family. (451 aa)

Predicted Functional Partners:

glyA

0.937

sync_1566

0.903

ilvA

0.900

trpA

0.900

trpB

0.900

sync_2013

0.814

cysE

0.800

metA

0.800

cbiG/cobJ

0.583

sync_2011

0.575

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbiG/cobJ	cobC	sync_0391	sync_2012	cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466.	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	0.583
cobC	cbiG/cobJ	sync_2012	sync_0391	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466.	0.583
cobC	cysE	sync_2012	sync_0087	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	0.800
cobC	glyA	sync_2012	sync_0300	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.937
cobC	ilvA	sync_2012	sync_1411	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.900
cobC	metA	sync_2012	sync_1181	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	0.800
cobC	sync_1566	sync_2012	sync_1566	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Serine:pyruvate/alanine:glyoxylate aminotransferase; Identified by match to protein family HMM PF00266; spt, agt.	0.903
cobC	sync_2011	sync_2012	sync_2011	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	CAAX amino terminal protease family protein; Identified by match to protein family HMM PF02517.	0.575
cobC	sync_2013	sync_2012	sync_2013	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Dihydroorotase, putative.	0.814
cobC	trpA	sync_2012	sync_1910	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.900
cobC	trpB	sync_2012	sync_2633	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.900
cysE	cobC	sync_0087	sync_2012	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	0.800
cysE	glyA	sync_0087	sync_0300	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.843
cysE	ilvA	sync_0087	sync_1411	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.812
cysE	sync_1566	sync_0087	sync_1566	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Serine:pyruvate/alanine:glyoxylate aminotransferase; Identified by match to protein family HMM PF00266; spt, agt.	0.800
cysE	trpA	sync_0087	sync_1910	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.813
cysE	trpB	sync_0087	sync_2633	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.812
glyA	cobC	sync_0300	sync_2012	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Possible alpha-ribazole-5-P phosphatase; Identified by match to protein family HMM PF00300; Belongs to the phosphoglycerate mutase family.	0.937
glyA	cysE	sync_0300	sync_0087	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Serine O-acetyltransferase; Identified by similarity to SP:Q06750; match to protein family HMM PF00132; match to protein family HMM TIGR01172.	0.843
glyA	ilvA	sync_0300	sync_1411	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.927