node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cbiD | cbiE/cbiT | sync_0046 | sync_0810 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | 0.997 |
cbiD | cbiG/cobJ | sync_0046 | sync_0391 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.999 |
cbiD | cobB | sync_0046 | sync_1000 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | 0.878 |
cbiD | cobD-1 | sync_0046 | sync_0724 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.878 |
cbiD | cobH | sync_0046 | sync_0078 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | precorrin-8X methylmutase; Identified by similarity to SP:P21638. | 0.947 |
cbiD | cobI | sync_0046 | sync_0590 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.905 |
cbiD | cobK | sync_0046 | sync_2025 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715. | 0.993 |
cbiD | cobM | sync_0046 | sync_2146 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family. | 0.943 |
cbiD | cobQ | sync_0046 | sync_0893 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.939 |
cbiD | cobS | sync_0046 | sync_0285 | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.726 |
cbiE/cbiT | cbiD | sync_0810 | sync_0046 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.997 |
cbiE/cbiT | cbiG/cobJ | sync_0810 | sync_0391 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466. | 0.999 |
cbiE/cbiT | cobB | sync_0810 | sync_1000 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | 0.940 |
cbiE/cbiT | cobD-1 | sync_0810 | sync_0724 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.941 |
cbiE/cbiT | cobH | sync_0810 | sync_0078 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | precorrin-8X methylmutase; Identified by similarity to SP:P21638. | 0.999 |
cbiE/cbiT | cobI | sync_0810 | sync_0590 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Precorrin-2 C20-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01467; Belongs to the precorrin methyltransferase family. | 0.993 |
cbiE/cbiT | cobK | sync_0810 | sync_2025 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Precorrin-6x reductase; Identified by match to protein family HMM PF02571; match to protein family HMM TIGR00715. | 0.997 |
cbiE/cbiT | cobM | sync_0810 | sync_2146 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Precorrin-4 C11-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465; Belongs to the precorrin methyltransferase family. | 0.999 |
cbiE/cbiT | cobQ | sync_0810 | sync_0893 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.942 |
cbiE/cbiT | cobS | sync_0810 | sync_0285 | Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.840 |