STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_2118Conserved hypothetical protein TIGR00303; Identified by match to protein family HMM PF02277; match to protein family HMM TIGR00303; Belongs to the UPF0284 family. (396 aa)    
Predicted Functional Partners:
sync_2117
Conserved hypothetical protein; Identified by similarity to GB:CAE21526.1.
 
     0.832
cbiG/cobJ
cbiG protein/precorrin-3B C17-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466.
 
  
 0.805
sync_2116
Conserved hypothetical protein.
       0.773
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
  
 
 0.749
sync_2119
Periplasmic binding protein-like II superfamily protein.
       0.710
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.653
cobD-2
L-threonine-O-3-phosphate decarboxylase; Identified by similarity to GB:AAC79515.1; match to protein family HMM PF00155; match to protein family HMM TIGR01140.
 
  
 0.652
cbiE/cbiT
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE/T subunits; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
  
  
 0.643
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.638
sync_1327
Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; Identified by match to protein family HMM PF02283.
  
  
 0.636
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
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