| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cugP | glmU | sync_2617 | sync_1533 | Nucleotidyl transferase family protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. | UDP-N-acetylglucosamine pyrophosphorylase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.878 |
| cugP | sync_0160 | sync_2617 | sync_0160 | Nucleotidyl transferase family protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.962 |
| cugP | sync_2133 | sync_2617 | sync_2133 | Nucleotidyl transferase family protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.800 |
| cyoE | drrB | sync_2129 | sync_2131 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | 0.673 |
| cyoE | sync_2130 | sync_2129 | sync_2130 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Drug exporter-1 ABC transporter (DrugE1) family, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01188. | 0.771 |
| cyoE | sync_2132 | sync_2129 | sync_2132 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Hypothetical protein. | 0.605 |
| cyoE | sync_2133 | sync_2129 | sync_2133 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.605 |
| cyoE | sync_2134 | sync_2129 | sync_2134 | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Hypothetical protein; Identified by Glimmer2; putative. | 0.564 |
| drrB | cyoE | sync_2131 | sync_2129 | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | 0.673 |
| drrB | sync_2130 | sync_2131 | sync_2130 | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | Drug exporter-1 ABC transporter (DrugE1) family, ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01188. | 0.998 |
| drrB | sync_2132 | sync_2131 | sync_2132 | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | Hypothetical protein. | 0.773 |
| drrB | sync_2133 | sync_2131 | sync_2133 | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.781 |
| drrB | sync_2134 | sync_2131 | sync_2134 | ABC-type multidrug transport system permease component; Identified by match to protein family HMM PF01061. | Hypothetical protein; Identified by Glimmer2; putative. | 0.718 |
| glmU | cugP | sync_1533 | sync_2617 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Nucleotidyl transferase family protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. | 0.878 |
| glmU | sync_0160 | sync_1533 | sync_0160 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.883 |
| glmU | sync_2133 | sync_1533 | sync_2133 | UDP-N-acetylglucosamine pyrophosphorylase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.862 |
| murQ | sync_2133 | sync_1386 | sync_2133 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.909 |
| murQ | sync_2639 | sync_1386 | sync_2639 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | N-acetylglucosamine-6-phosphate deacetylase. | 0.983 |
| sync_0160 | cugP | sync_0160 | sync_2617 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | Nucleotidyl transferase family protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. | 0.962 |
| sync_0160 | glmU | sync_0160 | sync_1533 | Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-N-acetylglucosamine pyrophosphorylase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.883 |