| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| gmk | guaA | sync_2153 | sync_0047 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.969 |
| gmk | ndk | sync_2153 | sync_2741 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.919 |
| gmk | purB | sync_2153 | sync_2334 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.921 |
| gmk | rpoZ | sync_2153 | sync_2269 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.788 |
| gmk | surE | sync_2153 | sync_0795 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| gmk | sync_1158 | sync_2153 | sync_1158 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Possible phosphoribosyltransferase family protein. | 0.900 |
| gmk | sync_1231 | sync_2153 | sync_1231 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | EF hand domain protein. | 0.805 |
| gmk | sync_1563 | sync_2153 | sync_1563 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231. | 0.738 |
| gmk | sync_2702 | sync_2153 | sync_2702 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.943 |
| gmk | sync_2880 | sync_2153 | sync_2880 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | 0.917 |
| guaA | gmk | sync_0047 | sync_2153 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
| guaA | ndk | sync_0047 | sync_2741 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.679 |
| guaA | purB | sync_0047 | sync_2334 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.919 |
| guaA | surE | sync_0047 | sync_0795 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.965 |
| guaA | sync_1158 | sync_0047 | sync_1158 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Possible phosphoribosyltransferase family protein. | 0.900 |
| guaA | sync_2880 | sync_0047 | sync_2880 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. | 0.906 |
| ndk | gmk | sync_2741 | sync_2153 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | 0.919 |
| ndk | guaA | sync_2741 | sync_0047 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.679 |
| ndk | sync_1231 | sync_2741 | sync_1231 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | EF hand domain protein. | 0.817 |
| ndk | sync_2702 | sync_2741 | sync_2702 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.915 |