sync_2271 protein (Synechococcus sp. CC9311)

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sync_2271

DnaK family protein; Belongs to the heat shock protein 70 family. (545 aa)

Predicted Functional Partners:

grpE-1

0.947

dnaJ-2

0.933

sync_0156

0.925

groS

0.920

htpG

0.917

dnaJ

0.907

groL1

0.897

groL2

0.896

sync_1388

0.826

sync_2345

0.771

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dnaJ	groL1	sync_2399	sync_2135	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.618
dnaJ	groL2	sync_2399	sync_2282	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.736
dnaJ	groS	sync_2399	sync_2283	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.677
dnaJ	grpE-1	sync_2399	sync_0022	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.889
dnaJ	htpG	sync_2399	sync_1398	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	Chaperone protein HtpG; Identified by similarity to SP:Q9S3Q2; match to protein family HMM PF00183; match to protein family HMM PF02518.	0.798
dnaJ	sync_0156	sync_2399	sync_0156	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746.	0.929
dnaJ	sync_2271	sync_2399	sync_2271	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	DnaK family protein; Belongs to the heat shock protein 70 family.	0.907
dnaJ-2	groL1	sync_0023	sync_2135	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.739
dnaJ-2	groL2	sync_0023	sync_2282	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.763
dnaJ-2	groS	sync_0023	sync_2283	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.730
dnaJ-2	grpE-1	sync_0023	sync_0022	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.983
dnaJ-2	htpG	sync_0023	sync_1398	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	Chaperone protein HtpG; Identified by similarity to SP:Q9S3Q2; match to protein family HMM PF00183; match to protein family HMM PF02518.	0.857
dnaJ-2	sync_0156	sync_0023	sync_0156	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746.	0.929
dnaJ-2	sync_2271	sync_0023	sync_2271	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	DnaK family protein; Belongs to the heat shock protein 70 family.	0.933
groL1	dnaJ	sync_2135	sync_2399	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	DnaJ3 protein; Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.	0.618
groL1	dnaJ-2	sync_2135	sync_0023	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]	0.739
groL1	groL2	sync_2135	sync_2282	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.903
groL1	groS	sync_2135	sync_2283	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.995
groL1	grpE-1	sync_2135	sync_0022	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.956
groL1	htpG	sync_2135	sync_1398	GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	Chaperone protein HtpG; Identified by similarity to SP:Q9S3Q2; match to protein family HMM PF00183; match to protein family HMM PF02518.	0.939