STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_2281Large-conductive mechanosensitive channel. (157 aa)    
Predicted Functional Partners:
groL2
GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
       0.773
mscL
Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220.
  
     0.769
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
   
  
 0.700
sync_2280
Ammonium transporter alr0992; Identified by match to protein family HMM PF00909.
     
 0.679
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.664
sync_2279
Ammonium transporter alr0992.
     
 0.657
groS
Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.576
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.414
sync_2278
Hypothetical protein; Identified by Glimmer2; putative.
       0.408
napA
Transporter, monovalent cation:proton antiporter-2 (CPA2) family protein; Identified by match to protein family HMM PF00582; match to protein family HMM PF00999.
     
 0.402
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
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