node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bioA | bioB | sync_2343 | sync_1032 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.983 |
bioA | bioD | sync_2343 | sync_2341 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.999 |
bioA | bioF | sync_2343 | sync_2338 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM TIGR00858. | 0.988 |
bioA | nadE | sync_2343 | sync_2294 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.536 |
bioA | ribAB | sync_2343 | sync_1383 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.525 |
bioA | sync_0156 | sync_2343 | sync_0156 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.840 |
bioA | sync_2337 | sync_2343 | sync_2337 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Superfamily II RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF08148. | 0.521 |
bioA | sync_2339 | sync_2343 | sync_2339 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Alpha/beta hydrolase family protein. | 0.694 |
bioA | sync_2340 | sync_2343 | sync_2340 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | SAM dependent methyltransferase. | 0.808 |
bioA | sync_2342 | sync_2343 | sync_2342 | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Identified by Glimmer2; putative. | 0.628 |
bioB | bioA | sync_1032 | sync_2343 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.983 |
bioB | bioD | sync_1032 | sync_2341 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.998 |
bioB | bioF | sync_1032 | sync_2338 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM TIGR00858. | 0.777 |
bioB | nadE | sync_1032 | sync_2294 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.453 |
bioB | ribAB | sync_1032 | sync_1383 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.529 |
bioB | sync_0156 | sync_1032 | sync_0156 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.843 |
bioD | bioA | sync_2341 | sync_2343 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Adenosylmethionine-8-amino-7-oxononanoate transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.999 |
bioD | bioB | sync_2341 | sync_1032 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.998 |
bioD | bioF | sync_2341 | sync_2338 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM TIGR00858. | 0.974 |
bioD | nadE | sync_2341 | sync_2294 | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.404 |