| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apt | guaA | sync_1226 | sync_0047 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.995 |
| apt | polA | sync_1226 | sync_0928 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.528 |
| apt | sync_0156 | sync_1226 | sync_0156 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.499 |
| apt | sync_0525 | sync_1226 | sync_0525 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein; Identified by similarity to GB:CAE21848.1; match to protein family HMM TIGR00201. | 0.674 |
| apt | sync_2414 | sync_1226 | sync_2414 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phage integrase family domain protein; Identified by match to protein family HMM PF00589. | 0.459 |
| apt | tyrA | sync_1226 | sync_0447 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Prephenate dehydrogenase; Identified by match to protein family HMM PF02153; match to protein family HMM PF02558; match to protein family HMM PF02737; match to protein family HMM PF03807. | 0.687 |
| guaA | apt | sync_0047 | sync_1226 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.995 |
| guaA | polA | sync_0047 | sync_0928 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.761 |
| guaA | sync_0156 | sync_0047 | sync_0156 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.753 |
| guaA | sync_2414 | sync_0047 | sync_2414 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Phage integrase family domain protein; Identified by match to protein family HMM PF00589. | 0.431 |
| polA | apt | sync_0928 | sync_1226 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.528 |
| polA | guaA | sync_0928 | sync_0047 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.761 |
| polA | sync_0156 | sync_0928 | sync_0156 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.826 |
| polA | sync_2414 | sync_0928 | sync_2414 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Phage integrase family domain protein; Identified by match to protein family HMM PF00589. | 0.429 |
| polA | sync_2415 | sync_0928 | sync_2415 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Bacteriophage protein homolog. | 0.894 |
| polA | topA | sync_0928 | sync_2114 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.900 |
| sync_0156 | apt | sync_0156 | sync_1226 | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.499 |
| sync_0156 | guaA | sync_0156 | sync_0047 | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.753 |
| sync_0156 | polA | sync_0156 | sync_0928 | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.826 |
| sync_0156 | sync_2414 | sync_0156 | sync_2414 | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | Phage integrase family domain protein; Identified by match to protein family HMM PF00589. | 0.451 |