| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| coaBC | coaD | sync_0352 | sync_1362 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.944 |
| coaBC | panC/cmk | sync_0352 | sync_0483 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.903 |
| coaBC | sync_2509 | sync_0352 | sync_2509 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.928 |
| coaD | coaBC | sync_1362 | sync_0352 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.944 |
| coaD | panC/cmk | sync_1362 | sync_0483 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.643 |
| coaD | sync_2509 | sync_1362 | sync_2509 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.931 |
| hflX | panC/cmk | sync_2512 | sync_0483 | GTP-binding protein HflX homolog; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.539 |
| hflX | sync_2509 | sync_2512 | sync_2509 | GTP-binding protein HflX homolog; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.642 |
| hflX | sync_2510 | sync_2512 | sync_2510 | GTP-binding protein HflX homolog; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.762 |
| hflX | sync_2511 | sync_2512 | sync_2511 | GTP-binding protein HflX homolog; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. | NADH dehydrogenase, FAD-containing subunit; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992. | 0.796 |
| hslO | sync_2509 | sync_1272 | sync_2509 | 33 kDa chaperonin (Heat shock protein 33 homolog) (HSP33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.441 |
| panC/cmk | coaBC | sync_0483 | sync_0352 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.903 |
| panC/cmk | coaD | sync_0483 | sync_1362 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.643 |
| panC/cmk | hflX | sync_0483 | sync_2512 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | GTP-binding protein HflX homolog; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. | 0.539 |
| panC/cmk | sync_1597 | sync_0483 | sync_1597 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Hypothetical protein; Identified by Glimmer2; putative. | 0.492 |
| panC/cmk | sync_2109 | sync_0483 | sync_2109 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | biotin--acetyl-CoA-carboxylase ligase; Identified by match to protein family HMM PF03099; match to protein family HMM TIGR00121. | 0.449 |
| panC/cmk | sync_2509 | sync_0483 | sync_2509 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.966 |
| panC/cmk | tmk | sync_0483 | sync_2593 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.505 |
| sync_1597 | panC/cmk | sync_1597 | sync_0483 | Hypothetical protein; Identified by Glimmer2; putative. | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.492 |
| sync_1597 | sync_2509 | sync_1597 | sync_2509 | Hypothetical protein; Identified by Glimmer2; putative. | Transcriptional activator, putative, Baf family protein; Identified by match to protein family HMM TIGR00671. | 0.551 |