| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| anmK | murQ | sync_2516 | sync_1386 | Predicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.986 |
| anmK | sync_0326 | sync_2516 | sync_0326 | Predicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | BadF/BadG/BcrA/BcrD ATPase family superfamily; Identified by match to protein family HMM PF01869. | 0.640 |
| anmK | sync_2563 | sync_2516 | sync_2563 | Predicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Possible beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF00933. | 0.814 |
| anmK | sync_2639 | sync_2516 | sync_2639 | Predicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylglucosamine-6-phosphate deacetylase. | 0.421 |
| hemD | rbfA | sync_2565 | sync_2562 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.692 |
| hemD | sync_0156 | sync_2565 | sync_0156 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.451 |
| hemD | sync_2560 | sync_2565 | sync_2560 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutathione S-transferase zeta class. | 0.511 |
| hemD | sync_2561 | sync_2565 | sync_2561 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Protein of unknown function (DUF751) family protein; Identified by match to protein family HMM PF05421. | 0.692 |
| hemD | sync_2563 | sync_2565 | sync_2563 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Possible beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF00933. | 0.677 |
| hemD | sync_2564 | sync_2565 | sync_2564 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glycosyl transferase, family 2:TPR repeat; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | 0.813 |
| murQ | anmK | sync_1386 | sync_2516 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | Predicted molecular chaperone; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.986 |
| murQ | sync_0326 | sync_1386 | sync_0326 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | BadF/BadG/BcrA/BcrD ATPase family superfamily; Identified by match to protein family HMM PF01869. | 0.796 |
| murQ | sync_2563 | sync_1386 | sync_2563 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | Possible beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF00933. | 0.673 |
| murQ | sync_2639 | sync_1386 | sync_2639 | Glucokinase regulator homolog; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | N-acetylglucosamine-6-phosphate deacetylase. | 0.981 |
| rbfA | hemD | sync_2562 | sync_2565 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.692 |
| rbfA | sync_2560 | sync_2562 | sync_2560 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Glutathione S-transferase zeta class. | 0.600 |
| rbfA | sync_2561 | sync_2562 | sync_2561 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Protein of unknown function (DUF751) family protein; Identified by match to protein family HMM PF05421. | 0.800 |
| rbfA | sync_2563 | sync_2562 | sync_2563 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Possible beta-N-acetylglucosaminidase; Identified by match to protein family HMM PF00933. | 0.815 |
| rbfA | sync_2564 | sync_2562 | sync_2564 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Glycosyl transferase, family 2:TPR repeat; Identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721. | 0.714 |
| sync_0156 | hemD | sync_0156 | sync_2565 | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.451 |