| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folE | moaA | sync_1986 | sync_2885 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | 0.906 |
| folE | ndk | sync_1986 | sync_2741 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.838 |
| folE | pyk | sync_1986 | sync_1415 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.813 |
| folE | ribAB | sync_1986 | sync_1383 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.957 |
| folE | sync_2620 | sync_1986 | sync_2620 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Adenylate cyclase; Identified by match to protein family HMM PF01928. | 0.800 |
| folE | sync_2702 | sync_1986 | sync_2702 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |
| folE | sync_2745 | sync_1986 | sync_2745 | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | Adenylate cyclase, putative; Identified by match to protein family HMM PF00211; match to protein family HMM PF05226. | 0.800 |
| moaA | folE | sync_2885 | sync_1986 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063. | 0.906 |
| moaA | ndk | sync_2885 | sync_2741 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
| moaA | pyk | sync_2885 | sync_1415 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.800 |
| moaA | ribAB | sync_2885 | sync_1383 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.903 |
| moaA | sync_2620 | sync_2885 | sync_2620 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Adenylate cyclase; Identified by match to protein family HMM PF01928. | 0.800 |
| moaA | sync_2702 | sync_2885 | sync_2702 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.802 |
| moaA | sync_2745 | sync_2885 | sync_2745 | Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. | Adenylate cyclase, putative; Identified by match to protein family HMM PF00211; match to protein family HMM PF05226. | 0.807 |
| nadK | ndhE | sync_2621 | sync_2622 | Predicted inorganic polyphosphate; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | NADH dehydrogenase I chain 4L or K; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration. | 0.772 |
| nadK | ribAB | sync_2621 | sync_1383 | Predicted inorganic polyphosphate; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.404 |
| nadK | sync_2620 | sync_2621 | sync_2620 | Predicted inorganic polyphosphate; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Adenylate cyclase; Identified by match to protein family HMM PF01928. | 0.800 |
| nadK | sync_2623 | sync_2621 | sync_2623 | Predicted inorganic polyphosphate; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | NADH-ubiquinone/plastoquinone oxidoreductase, subunit 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I subunit 6 family. | 0.733 |
| ndhE | nadK | sync_2622 | sync_2621 | NADH dehydrogenase I chain 4L or K; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration. | Predicted inorganic polyphosphate; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.772 |
| ndhE | sync_2620 | sync_2622 | sync_2620 | NADH dehydrogenase I chain 4L or K; NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration. | Adenylate cyclase; Identified by match to protein family HMM PF01928. | 0.772 |