| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaK | dnaK-1 | sync_1389 | sync_1293 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
| dnaK | dnaK-2 | sync_1389 | sync_2923 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
| dnaK | groL1 | sync_1389 | sync_2135 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.783 |
| dnaK | groL2 | sync_1389 | sync_2282 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.833 |
| dnaK | groS | sync_1389 | sync_2283 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.889 |
| dnaK | grpE-1 | sync_1389 | sync_0022 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.980 |
| dnaK | hrcA | sync_1389 | sync_2630 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.736 |
| dnaK-1 | dnaK | sync_1293 | sync_1389 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
| dnaK-1 | dnaK-2 | sync_1293 | sync_2923 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.901 |
| dnaK-1 | groL1 | sync_1293 | sync_2135 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.731 |
| dnaK-1 | groL2 | sync_1293 | sync_2282 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.731 |
| dnaK-1 | groS | sync_1293 | sync_2283 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.822 |
| dnaK-1 | grpE-1 | sync_1293 | sync_0022 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.967 |
| dnaK-1 | hrcA | sync_1293 | sync_2630 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.789 |
| dnaK-2 | dnaK | sync_2923 | sync_1389 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.903 |
| dnaK-2 | dnaK-1 | sync_2923 | sync_1293 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.901 |
| dnaK-2 | groL1 | sync_2923 | sync_2135 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL2 protein (Chaperonin cpn60-2); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.731 |
| dnaK-2 | groL2 | sync_2923 | sync_2282 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.731 |
| dnaK-2 | groS | sync_2923 | sync_2283 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.822 |
| dnaK-2 | grpE-1 | sync_2923 | sync_0022 | Chaperone protein dnaK2 (Heat shock protein 70-2) (Heat shock 70 kDaprotein 2) (HSP70-2); Acts as a chaperone; Belongs to the heat shock protein 70 family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.967 |