STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_2656Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. (491 aa)    
Predicted Functional Partners:
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
 0.988
sync_2801
Conserved hypothetical protein; Identified by similarity to GB:CAE22353.1.
     
 0.910
sync_0154
Membrane protein, putative.
  
  
 0.889
sync_0462
Putative anthranilate synthase component I; Identified by similarity to SP:P20579; match to protein family HMM PF00425; match to protein family HMM PF04715.
  
  
0.873
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.872
tyrA
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153; match to protein family HMM PF02558; match to protein family HMM PF02737; match to protein family HMM PF03807.
     
 0.835
aspC
Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.
    
  0.802
aroH
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
     
  0.800
hisC
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141.
     
 0.800
menA
1,4-dihydroxy-2-naphthoate phytyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily.
 
   
 0.780
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
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