| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| era | ndk | sync_0773 | sync_2741 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.658 |
| era | sync_0768 | sync_0773 | sync_0768 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Identified by match to protein family HMM PF02562. | 0.607 |
| era | sync_2846 | sync_0773 | sync_2846 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.549 |
| glpK | sync_2846 | sync_0569 | sync_2846 | Glycerol kinase; Identified by match to protein family HMM PF00370; match to protein family HMM PF02782; Belongs to the FGGY kinase family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.606 |
| gpmI | sync_2846 | sync_2276 | sync_2846 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.591 |
| hisIE | sync_2846 | sync_1899 | sync_2846 | Histidine biosynthesis bifunctional protein HisIE; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.519 |
| ndk | era | sync_2741 | sync_0773 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.658 |
| ndk | panC/cmk | sync_2741 | sync_0483 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | 0.944 |
| ndk | sync_2846 | sync_2741 | sync_2846 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.500 |
| panC/cmk | ndk | sync_0483 | sync_2741 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.944 |
| panC/cmk | sync_2846 | sync_0483 | sync_2846 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.519 |
| panC/cmk | thyX | sync_0483 | sync_0320 | Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.600 |
| polA | sync_2846 | sync_0928 | sync_2846 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.583 |
| sync_0768 | era | sync_0768 | sync_0773 | Identified by match to protein family HMM PF02562. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.607 |
| sync_0768 | sync_2846 | sync_0768 | sync_2846 | Identified by match to protein family HMM PF02562. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.490 |
| sync_2845 | sync_2846 | sync_2845 | sync_2846 | Conserved hypothetical protein. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.603 |
| sync_2846 | era | sync_2846 | sync_0773 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.549 |
| sync_2846 | glpK | sync_2846 | sync_0569 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Glycerol kinase; Identified by match to protein family HMM PF00370; match to protein family HMM PF02782; Belongs to the FGGY kinase family. | 0.606 |
| sync_2846 | gpmI | sync_2846 | sync_2276 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.591 |
| sync_2846 | hisIE | sync_2846 | sync_1899 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Histidine biosynthesis bifunctional protein HisIE; Identified by similarity to SP:O34912; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family. | 0.519 |