| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argD | metH | sync_0744 | sync_1353 | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.428 |
| argD | proC | sync_0744 | sync_0601 | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.505 |
| argD | speB | sync_0744 | sync_2851 | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | 0.600 |
| argD | sync_0156 | sync_0744 | sync_0156 | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.669 |
| leuS | metH | sync_1375 | sync_1353 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.588 |
| leuS | speB | sync_1375 | sync_2851 | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | 0.512 |
| metH | argD | sync_1353 | sync_0744 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.428 |
| metH | leuS | sync_1353 | sync_1375 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.588 |
| metH | speB | sync_1353 | sync_2851 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | 0.414 |
| metH | sync_0156 | sync_1353 | sync_0156 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.657 |
| proC | argD | sync_0601 | sync_0744 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.505 |
| proC | speA | sync_0601 | sync_2742 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | 0.473 |
| proC | speB | sync_0601 | sync_2851 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | 0.546 |
| proC | sync_0156 | sync_0601 | sync_0156 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.613 |
| speA | proC | sync_2742 | sync_0601 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.473 |
| speA | speB | sync_2742 | sync_2851 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | 0.959 |
| speA | speE | sync_2742 | sync_2850 | Arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.673 |
| speB | argD | sync_2851 | sync_0744 | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | Acetylornithine aminotransferase (ACOAT); Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00707; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.600 |
| speB | leuS | sync_2851 | sync_1375 | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.512 |
| speB | metH | sync_2851 | sync_1353 | Agmatinase; Identified by similarity to SP:P70999; match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.414 |
