STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_2880Glutamine amidotransferase, class I; Identified by match to protein family HMM PF00117. (255 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.929
surE
Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.916
gmk
Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.916
sync_0971
Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304.
  
 
 0.911
guaA
GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.
    
 0.906
rdgB
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.902
sync_1158
Possible phosphoribosyltransferase family protein.
     
  0.900
sync_2846
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
  0.900
ureB
Urease, beta subunit; Identified by similarity to SP:P74386; match to protein family HMM PF00699; match to protein family HMM TIGR00192; Belongs to the urease beta subunit family.
       0.773
ureC
Urease, alpha subunit; Identified by similarity to SP:P18314; match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
       0.773
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.