Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AGA84877.1Sulfur carrier protein ThiS; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS. (66 aa)    
Predicted Functional Partners:
thiG
Putative enzyme of thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
AGA85679.1
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.
  
 
 0.964
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.947
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.932
AGA85696.1
8-oxo-dGTPase; PFAM: NUDIX domain; Thiamine monophosphate synthase/TENI; TIGRFAM: mutator mutT protein; thiamine-phosphate pyrophosphorylase.
 
  
 0.924
AGA85144.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; manually curated.
 
  
 0.922
AGA87962.1
Hypothetical protein.
  
    0.792
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.657
AGA84876.1
Uncharacterized small membrane protein; PFAM: Protein of unknown function (DUF423).
       0.621
AGA87858.1
Glycine oxidase; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO.
 
  
 0.621
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
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