Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGA85092.1PFAM: Retroviral aspartyl protease; TIGRFAM: clan AA aspartic protease, TIGR02281 family. (175 aa)    
Predicted Functional Partners:
AGA85091.1
Hypothetical protein.
  
    0.826
parE
DNA topoisomerase IV, B subunit, proteobacterial; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
  
    0.807
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
  
    0.807
AGA85089.1
Putative esterase; PFAM: Uncharacterised protein family (UPF0227).
  
    0.677
AGA85094.1
PFAM: Protein of unknown function (DUF330).
       0.512
AGA87736.1
PFAM: Protein of unknown function (DUF2726).
  
     0.495
cpdA
Putative phosphohydrolase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.459
AGA88053.1
PFAM: Protein of unknown function (DUF3299).
  
     0.443
AGA85087.1
PFAM: Protein of unknown function (DUF1249).
 
     0.441
AGA88119.1
Putative membrane protein; PFAM: Protein of unknown function (DUF805).
  
     0.432
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.