STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AGA86519.1Hypothetical protein; Manually curated. (205 aa)    
Predicted Functional Partners:
AGA86518.1
nucleotidyltransferase/DNA polymerase involved in DNA repair; PFAM: impB/mucB/samB family.
 
  
 0.998
dnaE2
DNA-directed DNA polymerase III PolC; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.975
dinB
nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.877
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.754
AGA87332.1
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
  
 0.576
AGA85540.1
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.501
AGA88241.1
PFAM: Protein of unknown function, DUF484.
  
     0.475
AGA88413.1
PFAM: Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn); TIGRFAM: putative polyhydroxyalkanoic acid system protein.
  
     0.474
AGA84804.1
Hypothetical protein; PFAM: Domain of unknown function (DUF2383); TIGRFAM: conserved hypothetical protein.
  
     0.461
AGA84798.1
Metal-dependent hydrolase; PFAM: Endonuclease/Exonuclease/phosphatase family.
  
     0.406
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.