STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflDUncharacterized protein involved in purine metabolism; PFAM: Protein of unknown function (DUF489). (212 aa)    
Predicted Functional Partners:
mnmA
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.979
AGA86553.1
PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.793
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
   
    0.765
AGA86552.1
PFAM: Cupin superfamily protein.
 
  
 0.755
nudJ
ADP-ribose pyrophosphatase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family. NudJ subfamily.
  
    0.750
rnt
RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
    0.706
AGA87493.1
Hypothetical protein; PFAM: YcgL domain.
  
  
 0.698
AGA86549.1
Type II secretory pathway, component PulD; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein.
       0.643
AGA86550.1
Hypothetical protein.
       0.643
AGA86551.1
Putative acyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.643
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.