Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGA86844.12-methylaconitate cis-trans isomerase; PFAM: PrpF protein; TIGRFAM: probable AcnD-accessory protein PrpF. (395 aa)    
Predicted Functional Partners:
AGA86845.1
Aconitate hydratase 1/2-methylisocitrate dehydratase, Fe/S-dependent; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.998
AGA87043.1
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.987
AGA86846.1
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
 
  
 0.967
AGA86835.1
Aconitate hydratase 2; PFAM: Aconitate B N-terminal domain; Aconitase family (aconitate hydratase); Aconitate hydratase 2 N-terminus; TIGRFAM: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
    
 0.917
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
  
 0.904
AGA86848.1
PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.755
AGA85158.1
PEP phosphonomutase-like enzyme; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.
 
  
 0.726
AGA87182.1
Uncharacterized protein involved in propionate catabolism; PFAM: MmgE/PrpD family.
 
  
 0.653
AGA87021.1
PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
  
 0.586
AGA86850.1
Hypothetical protein.
       0.533
Your Current Organism:
Pseudomonas stutzeri
NCBI taxonomy Id: 644801
Other names: P. stutzeri RCH2, Pseudomonas stutzeri RCH2, Pseudomonas stutzeri str. RCH2, Pseudomonas stutzeri strain RCH2
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