STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Tmar_0082Transcriptional regulator, AbrB family; COGs: COG2002 Regulators of stationary/sporulation gene expression; InterPro IPR007159: IPR006339; KEGG: sth:STH3253 sporulation-related transcriptional regulator AbrB; PFAM: SpoVT/AbrB domain-containing protein; SPTR: Sporulation-related transcriptional regulator AbrB; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family. (83 aa)    
Predicted Functional Partners:
Tmar_1157
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.806
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.750
Tmar_1106
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.690
Tmar_1831
InterPro IPR004995; KEGG: pjd:Pjdr2_2911 GerA spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein.
  
     0.685
Tmar_1295
InterPro IPR004995; KEGG: tpd:Teth39_0180 GerA spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein.
  
     0.673
Tmar_0876
InterPro IPR014202; KEGG: bts:Btus_3254 stage II sporulation protein R; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
     0.670
Tmar_0066
GerA spore germination protein; InterPro IPR004995; KEGG: bbe:BBR47_36580 putative spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein.
  
     0.659
Tmar_0174
Sporulation transcriptional regulator SpoIIID; InterPro IPR014208: IPR018356; KEGG: sth:STH103 stage III sporulation protein D; SPTR: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
   
 0.653
Tmar_1138
SpoVA protein; InterPro IPR005562; KEGG: slp:Slip_0528 stage V sporulation protein AC; PFAM: SpoVA protein; SPTR: Stage V sporulation protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
  
     0.623
Tmar_0104
Sporulation protein YabP; InterPro IPR012504; KEGG: sth:STH3228 hypothetical protein; PFAM: YabP family protein; SPTR: Sporulation protein YabP; TIGRFAM: sporulation protein YabP; PFAM: YabP family; TIGRFAM: sporulation protein YabP.
  
   
 0.618
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.