STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0090KEGG: adg:Adeg_2095 hypothetical protein; SPTR: Putative uncharacterized protein. (270 aa)    
Predicted Functional Partners:
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.796
Tmar_0091
Purine operon repressor, PurR; COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR015265: IPR000836: IPR010078; KEGG: sth:STH3244 pur operon repressor; PFAM: purine repressor; phosphoribosyltransferase; SPTR: Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: Phosphoribosyl transferase domain; Bacterial purine repressor, N-terminal; TIGRFAM: pur operon repressor, Bacillus subtilis type.
  
    0.779
Tmar_0143
KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.775
ispE
4-diphosphocytidyl-2C-methyl-D-erythritolkinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
     
 0.756
Tmar_2122
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: sth:STH766 putative transcriptional regulator; PFAM: helix-turn-helix domain protein; SPTR: Putative transcriptional regulator; PFAM: Helix-turn-helix.
  
     0.756
Tmar_2059
Stage II sporulation protein P; InterPro IPR010897: IPR011672; KEGG: tjr:TherJR_1588 stage II sporulation protein P; PFAM: Stage II sporulation P family protein; protein of unknown function DUF1614; SPTR: Stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); Protein of unknown function (DUF1614); TIGRFAM: stage II sporulation protein P.
  
     0.727
Tmar_1110
KEGG: swo:Swol_1336 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3189).
  
     0.670
Tmar_2192
Membrane protein of unknown function; InterPro IPR007165; KEGG: hor:Hore_12870 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: Putative uncharacterized protein; PFAM: Membrane protein of unknown function.
  
     0.645
Tmar_1059
Hypothetical protein; InterPro IPR005829; KEGG: adg:Adeg_0624 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.631
Tmar_0092
L-threonine ammonia-lyase; COGs: COG1171 Threonine dehydratase; InterPro IPR001926: IPR002912: IPR005789: IPR017975; KEGG: drm:Dred_0097 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form.
 
     0.618
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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