STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0149InterPro IPR000209; KEGG: sth:STH62 putative serine protease; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; SPTR: Putative serine protease; PFAM: Subtilase family. (1368 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
    0.592
Tmar_0908
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterPro IPR004014: IPR008250: IPR005834: IPR006068: IPR 001757: IPR000695: IPR018303; KEGG: sth:STH1335 cation-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehaloge [...]
   
 0.460
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.444
Tmar_0148
KEGG: sco:SCO2669 hypothetical protein; SPTR: Major ampullate gland dragline silk protein-1.
       0.439
Tmar_0400
KEGG: lma:LmjF35.0290 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.428
Tmar_1594
KEGG: tmz:Tmz1t_0364 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.428
Tmar_1700
Peptidase M36 fungalysin; InterPro IPR000421: IPR011096: IPR001842; KEGG: rxy:Rxyl_2538 coagulation factor 5/8 type-like protein; PFAM: peptidase M36 fungalysin; Propeptide peptidase M4 and M36; coagulation factor 5/8 type domain protein; SPTR: Coagulation factor 5/8 type-like protein; PFAM: F5/8 type C domain; Fungalysin/Thermolysin Propeptide Motif; Fungalysin metallopeptidase (M36).
  
 
 0.428
Tmar_1918
Hypothetical protein; InterPro IPR001014; KEGG: cgr:CAGL0J02552g hypothetical protein; SPTR: Strain CBS138 chromosome J complete sequence.
  
 
 0.428
Tmar_2028
KEGG: aba:Acid345_0296 hypothetical protein; SPTR: Endo-1,4-beta-glucanase.
  
 
 0.428
Tmar_2168
KEGG: tjr:TherJR_2420 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3048).
  
 
 0.428
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.