STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0174Sporulation transcriptional regulator SpoIIID; InterPro IPR014208: IPR018356; KEGG: sth:STH103 stage III sporulation protein D; SPTR: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID. (99 aa)    
Predicted Functional Partners:
Tmar_1180
Stage III sporulation protein AE; InterPro IPR014194; KEGG: dau:Daud_1011 hypothetical protein; PFAM: Sporulation stage III protein AE; SPTR: Putative uncharacterized protein; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
  
    0.951
Tmar_1106
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.883
Tmar_0876
InterPro IPR014202; KEGG: bts:Btus_3254 stage II sporulation protein R; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.862
Tmar_0132
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR010822; KEGG: sth:STH3200 stage II sporulation protein E; PFAM: Stage II sporulation protein E; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation protein E; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E.
  
   
 0.861
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.852
Tmar_1184
AAA ATPase; COGs: COG3854 conserved hypothetical protein; InterPro IPR003593: IPR000209; KEGG: mta:Moth_1536 hypothetical protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; TIGRFAM: stage III sporulation protein AA.
  
   
 0.852
Tmar_0101
Transcriptional regulator, AbrB family; InterPro IPR007159: IPR014213: IPR006339; KEGG: tjr:TherJR_0180 transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein; SPTR: Transcriptional regulator, AbrB family; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T.
  
  
 0.850
Tmar_1275
Transcriptional regulator, AbrB family; InterPro IPR007159: IPR003018: IPR006339; KEGG: hmo:HM1_0719 stage V sporulation protein T, AbrB family transcriptional regulator; PFAM: SpoVT/AbrB domain-containing protein; GAF domain protein; SPTR: Stage v sporulation protein t, abrb family transcriptional regulator; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T.
  
  
 0.850
Tmar_1157
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.846
Tmar_0350
InterPro IPR010897; KEGG: sth:STH481 stage II sporulation protein P; PFAM: Stage II sporulation P family protein; SPTR: Stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P.
  
  
 0.845
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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