STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0265Phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122: IPR005273; KEGG: sth:STH2917 uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Uracil-DNA glycosylase; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4. (333 aa)    
Predicted Functional Partners:
Tmar_0543
COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122; KEGG: tro:trd_A0197 uracil-DNA glycosylase superfamily; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Uracil-DNA glycosylase superfamily; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
  
  
 
0.912
Tmar_0267
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: rsq:Rsph17025_2280 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22, glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
  
    0.880
Tmar_0266
Uncharacterized protein family UPF0079, ATPase; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: hmo:HM1_1717 hypothetical protein; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family.
 
     0.833
Tmar_0268
COGs: COG0456 Acetyltransferase; InterPro IPR000182: IPR006464; KEGG: aac:Aaci_0371 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; PRIAM: Ribosomal-protein-alanine N-acetyltransferase; SPTR: Ribosomal-protein-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase.
  
    0.671
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.611
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.605
Tmar_0264
COGs: COG4448 L-asparaginase II; InterPro IPR010349; KEGG: ttj:TTHA0067 L-asparaginase II; PFAM: L-asparaginase II; SPTR: L-asparaginase II; PFAM: L-asparaginase II.
       0.584
Tmar_0262
KEGG: pan:PODANSg7335 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.457
Tmar_0263
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
       0.457
Tmar_0270
Hypothetical protein; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: pth:PTH_2726 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats).
       0.457
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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