STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
moaCGTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (204 aa)    
Predicted Functional Partners:
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
Tmar_2085
COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR010034: IPR010038: IPR003749: IPR003448; KEGG: sth:STH3180 molybdopterin converting factor-like protein; PFAM: molybdopterin biosynthesis MoaE protein; thiamineS protein; SPTR: Molybdopterin converting factor; TIGRFAM: molybdopterin converting factor, subunit 1; MoaD family protein; PFAM: ThiS family; MoaE protein; TIGRFAM: MoaD family protein, archaeal; molybdopterin converting factor, subunit 1, non-archaeal.
 
 0.999
Tmar_0277
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR008284; KEGG: bts:Btus_1305 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
  
 0.998
Tmar_0622
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.997
Tmar_0275
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.990
Tmar_1103
MoaD family protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR001763: IPR010038: IPR003749: IPR000594: IPR 007901; KEGG: ttr:Tter_1313 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; thiamineS protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Putative Molybdopterin biosynthesis protein moeB (Modular protein); TIGRFAM: MoaD family protein; PFAM: ThiS family; MoeZ/MoeB domain; Rhodanese-like domain; ThiF family; TIGRFAM: MoaD [...]
 
  
 0.933
Tmar_0467
Molybdenum ABC transporter, periplasmic molybdate-binding protein; COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR017975: IPR005950: IPR006059; KEGG: gct:GC56T3_0789 molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Molybdenum ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: Bacterial extracellular solute-binding protein; LysR substrate binding domain; TIGRFAM: molybdenum ABC transporte [...]
 
   
 0.757
Tmar_0468
Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
   
 0.732
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
   
 0.715
Tmar_1453
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: nca:Noca_3027 indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase.
    
 0.656
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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