STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0350InterPro IPR010897; KEGG: sth:STH481 stage II sporulation protein P; PFAM: Stage II sporulation P family protein; SPTR: Stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation protein P (SpoIIP); TIGRFAM: stage II sporulation protein P. (292 aa)    
Predicted Functional Partners:
Tmar_1106
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
   
 0.846
Tmar_0174
Sporulation transcriptional regulator SpoIIID; InterPro IPR014208: IPR018356; KEGG: sth:STH103 stage III sporulation protein D; SPTR: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
  
 0.845
Tmar_0876
InterPro IPR014202; KEGG: bts:Btus_3254 stage II sporulation protein R; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.844
Tmar_0132
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR010822; KEGG: sth:STH3200 stage II sporulation protein E; PFAM: Stage II sporulation protein E; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation protein E; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E.
  
   
 0.843
Tmar_1184
AAA ATPase; COGs: COG3854 conserved hypothetical protein; InterPro IPR003593: IPR000209; KEGG: mta:Moth_1536 hypothetical protein; SMART: AAA ATPase; SPTR: Putative uncharacterized protein; TIGRFAM: stage III sporulation protein AA.
  
   
 0.833
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.825
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
 
    0.816
Tmar_1157
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.815
Tmar_1158
Stage IV sporulation protein B; InterPro IPR001478: IPR014219: IPR008763; KEGG: sth:STH1833 stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; PDZ/DHR/GLGF domain protein; PRIAM: SpoIVB peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Stage IV sporulation protein B; TIGRFAM: stage IV sporulation protein B; PFAM: SpoIVB peptidase S55; TIGRFAM: stage IV sporulation protein B.
  
   
 0.799
Tmar_1137
InterPro IPR010894; KEGG: pth:PTH_1229 stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; SPTR: Putative uncharacterized protein; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
   
 0.788
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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