STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Tmar_0440Putative sodium symporter protein; COGs: COG4147 symporter; InterPro IPR001734: IPR018247: IPR019899: IPR019900; KEGG: sth:STH2322 Ssf family Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Ssf family Na+/solute symporter; TIGRFAM: putative sodium symporter protein; SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: probable sodium:solute symporter, VC_2705 subfamily; transporter, SSS family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (600 aa)    
Predicted Functional Partners:
Tmar_0441
Putative solute symporter protein; COGs: COG4327 membrane protein; InterPro IPR019886; KEGG: sth:STH2323 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: putative solute symporter protein; TIGRFAM: probable solute:sodium symporter small subunit.
 
    0.932
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.592
Tmar_0439
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR004358: IPR005467: IPR003018: IPR003594: IPR 010559; KEGG: adg:Adeg_1762 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain.
       0.435
Tmar_1293
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845: IPR000873; KEGG: chy:CHY_0572 acetyl-coenzyme A synthetase family protein; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetyl-coenzyme A synthetase family protein; manually curated; PFAM: AMP-binding enzyme.
  
  
 0.413
Tmar_1483
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: sti:Sthe_2025 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme.
  
  
 0.413
Tmar_1744
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: rxy:Rxyl_1711 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase.
  
  
 0.413
Tmar_2008
acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR005914: IPR017975: IPR020845: IPR000873; KEGG: bts:Btus_1007 acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase.
  
  
 0.413
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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