STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_0568COGs: COG4623 soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein; InterPro IPR000189: IPR008258; KEGG: bts:Btus_0590 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain. (309 aa)    
Predicted Functional Partners:
Tmar_0195
COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492: IPR013384; KEGG: tjr:TherJR_2797 flagellar hook-associated protein 3; PFAM: flagellin domain protein; SPTR: Flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3.
 
 
 0.739
Tmar_0185
Flagellar hook-associated 2 domain-containing protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
  
 0.631
Tmar_0692
OmpA/MotB domain protein; COGs: COG1360 Flagellar motor protein; InterPro IPR006665: IPR006664; KEGG: chy:CHY_0964 flagellar motor protein MotB; PFAM: OmpA/MotB domain protein; SPTR: OmpA/MotB domain protein; PFAM: OmpA family.
 
  
 0.568
Tmar_0981
Type III secretion system ATPase, FliI/YscN; COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterPro IPR003593: IPR005714: IPR020003: IPR004100: IPR 000194; KEGG: hmo:HM1_2224 flagellar protein export ATPase FliI, putative; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase; SPTR: Flagellar protein export ATPase FliI; TIGRFAM: ATPase, FliI/YscN family; PFAM: ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family.
  
  
 0.552
fliE
COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sth:STH3004 flagellar hook-basal body protein; PFAM: flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body protein; TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE.
  
  
 0.539
Tmar_0567
Histidinol phosphate phosphatase HisJ family; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; InterPro IPR010140: IPR011659: IPR004013; KEGG: sth:STH906 acylaminoacyl-peptidase; PFAM: PHP domain protein; WD40-like beta Propeller containing protein; SPTR: Acylaminoacyl-peptidase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat; TIGRFAM: histidinol phosphate phosphatase HisJ family.
       0.508
Tmar_0152
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: ade:Adeh_1347 peptidase M23B; PFAM: Peptidase M23; SPTR: Peptidase M23B; PFAM: Peptidase family M23.
   
 0.507
Tmar_1243
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   0.505
Tmar_0985
COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR020013: IPR019776: IPR001444: IPR011491: IPR 010930; KEGG: tjr:TherJR_1533 fagellar hook-basal body protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; flagellar basal body rod protein; SPTR: Fagellar hook-basal body protein; TIGRFAM: fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgB.
  
  
 0.490
Tmar_0988
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: ate:Athe_2161 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
  
    0.486
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.