STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1080AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593: IPR003959: IPR000641; KEGG: sth:STH1745 stage V sporulation protein K; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: stage V sporulation protein K. (342 aa)    
Predicted Functional Partners:
Tmar_1079
GTP-binding protein HSR1-related protein; InterPro IPR002917; KEGG: hor:Hore_11600 GTP-binding conserved hypothetical protein TIGR00650; PFAM: GTP-binding protein HSR1-related; SPTR: Putative uncharacterized protein; PFAM: GTPase of unknown function.
 
     0.866
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
  0.813
Tmar_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.810
Tmar_2229
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110: IPR020683; KEGG: tpe:Tpen_1284 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: Ankyrin; PFAM: Ankyrin repeat.
    
 0.779
Tmar_1078
KEGG: aac:Aaci_1568 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.754
Tmar_0798
KEGG: acp:A2cp1_2337 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: impB/mucB/samB family.
     
 0.724
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
     
 0.724
Tmar_1077
KEGG: aac:Aaci_1569 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.714
Tmar_0450
Peptidase M28; InterPro IPR007484; KEGG: sth:STH1635 hypothetical protein; PFAM: peptidase M28; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M28.
     
 0.699
Tmar_0388
Band 7 protein; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: gwc:GWCH70_0387 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family.
   
 0.679
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.