STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scpBCondensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (236 aa)    
Predicted Functional Partners:
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
 
 
 0.999
cmk
COGs: COG0283 Cytidylate kinase; InterPro IPR003136: IPR000623: IPR011994; KEGG: sth:STH1668 cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 0.966
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.858
Tmar_1122
Ribosomal large subunit pseudouridine synthase B; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR000748: IPR018496: IPR006145; KEGG: adg:Adeg_1292 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.774
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.686
Tmar_1134
Peptidase M50; COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: adg:Adeg_1301 peptidase M50; PFAM: peptidase M50; SPTR: Peptidase M50; PFAM: Peptidase family M50.
       0.682
Tmar_1131
KEGG: sth:STH1800 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.601
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
  
 0.524
Tmar_1079
GTP-binding protein HSR1-related protein; InterPro IPR002917; KEGG: hor:Hore_11600 GTP-binding conserved hypothetical protein TIGR00650; PFAM: GTP-binding protein HSR1-related; SPTR: Putative uncharacterized protein; PFAM: GTPase of unknown function.
  
  
 0.506
Tmar_1130
Sporulation protein YtfJ; COGs: COG3874 conserved hypothetical protein; InterPro IPR014229; KEGG: tjr:TherJR_1631 sporulation protein YtfJ; PFAM: Sporulation protein YtfJ; SPTR: Sporulation protein YtfJ; TIGRFAM: sporulation protein YtfJ; PFAM: Sporulation protein YtfJ (Spore_YtfJ); TIGRFAM: sporulation protein YtfJ.
       0.493
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.