STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1276Protein of unknown function DUF965; COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: adg:Adeg_1439 hypothetical protein; PFAM: protein of unknown function DUF965; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF965). (169 aa)    
Predicted Functional Partners:
Tmar_1219
Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the UPF0473 family. Belongs to the YqgF nuclease family.
 
  
 0.988
Tmar_2356
Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: mta:Moth_0126 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951).
  
     0.733
Tmar_2074
Protein of unknown function DUF633; COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: hmo:HM1_1997 hypothetical protein; PFAM: protein of unknown function DUF633; SPTR: Putative uncharacterized protein; PFAM: Family of unknown function (DUF633).
  
     0.708
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
  
 0.671
Tmar_0956
Helix-turn-helix protein YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.671
Tmar_1277
KEGG: drm:Dred_0612 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.636
Tmar_0928
Protein of unknown function DUF322; COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: tjr:TherJR_2102 protein of unknown function DUF322; PFAM: protein of unknown function DUF322; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322).
  
    0.589
Tmar_2312
RNA polymerase, sigma 30 subunit, SigH; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR016371: IPR007627: IPR013249: IPR000792: IPR 000943: IPR014218: IPR014284; KEGG: sth:STH3113 RNA polymerase factor sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Stage 0 sporulation protein H, RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymera [...]
  
     0.494
Tmar_0896
COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616: IPR008532; KEGG: sth:STH1332 fibronectin-binding protein; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Fibronectin-binding protein; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA).
  
     0.480
Tmar_1278
Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR020578: IPR016454: IPR000192; KEGG: mta:Moth_0199 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase, class V; PFAM: Aminotransferase class-V.
       0.469
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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