STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1327COGs: COG4721 membrane protein; InterPro IPR017195; KEGG: esi:Exig_1584 YkoE; PFAM: ABC-type thiamin-related transport system, permease component 1, predicted; SPTR: Putative uncharacterized protein ykoE; PFAM: ABC-type cobalt transport system, permease component. (198 aa)    
Predicted Functional Partners:
Tmar_1326
ABC transporter related protein; COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR017871: IPR003439: IPR003339: IPR003593; KEGG: aac:Aaci_0945 ABC transporter related; PFAM: ABC transporter related; cobalt transport protein; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; Cobalt transport protein.
 
  
 0.988
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
    0.832
Tmar_1325
Transcriptional activator, TenA family; COGs: COG0819 Putative transcription activator; InterPro IPR004305; KEGG: npu:Npun_R3311 TenA family transcription regulator; PFAM: TENA/THI-4 domain-containing protein; SPTR: TENA/THI-4 family; PFAM: TENA/THI-4/PQQC family.
 
    0.721
Tmar_2264
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: sth:STH3043 cobalt ABC transporter permease protein; PFAM: cobalt transport protein; SPTR: Cobalt ABC transporter permease protein; PFAM: Cobalt transport protein.
  
  
 0.590
Tmar_1992
Transcriptional activator, TenA family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
    0.557
Tmar_1978
Phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399: IPR013749; KEGG: bts:Btus_2614 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; pyridoxal kinase.
  
    0.480
Tmar_0821
Protein of unknown function YwhD; InterPro IPR014852; KEGG: gym:GYMC10_0095 hypothetical protein; PFAM: protein of unknown function YwhD; SPTR: Putative uncharacterized protein; PFAM: YwhD family.
  
     0.409
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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