STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1374Branched-chain amino acid transport; COGs: COG4392 membrane protein; InterPro IPR008407; KEGG: sth:STH456 hypothetical protein; PFAM: branched-chain amino acid transport; SPTR: Putative uncharacterized protein; PFAM: Branched-chain amino acid transport protein (AzlD). (107 aa)    
Predicted Functional Partners:
Tmar_1375
AzlC family protein; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: dma:DMR_42190 AzlC-like family protein; PFAM: AzlC family protein; SPTR: AzlC family protein; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC.
 
  
 0.964
Tmar_1376
NUDIX hydrolase; InterPro IPR020084: IPR000086; KEGG: sth:STH892 hypothetical protein; PFAM: NUDIX hydrolase; SPTR: Putative uncharacterized protein; PFAM: NUDIX domain.
       0.482
Tmar_1377
Peptidase M20; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933: IPR011650; KEGG: cag:Cagg_1901 peptidase M20; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Peptidase M20; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain.
       0.476
Tmar_1372
Two component transcriptional regulator, LuxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792: IPR001789; KEGG: sth:STH921 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family.
       0.437
Tmar_1373
COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005467: IPR003660: IPR011712: IPR003594: IPR 004358; KEGG: sth:STH920 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Two-component sensor histidine kinase; PFAM: Histidine kinase; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
       0.437
Tmar_1371
Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
       0.401
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.