STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1513COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160: IPR015590; KEGG: bts:Btus_1063 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family. (552 aa)    
Predicted Functional Partners:
Tmar_0589
COGs: COG0506 Proline dehydrogenase; InterPro IPR008219: IPR002872; KEGG: bts:Btus_0836 proline dehydrogenase; PFAM: Proline dehydrogenase; PRIAM: Proline dehydrogenase; SPTR: Proline dehydrogenase; PFAM: Proline dehydrogenase.
 
 
 0.933
Tmar_1825
Amidase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR020556: IPR000120; KEGG: dol:Dole_2535 amidase; PFAM: Amidase; SPTR: Amidase; PFAM: Amidase; Belongs to the amidase family.
   
 0.905
def
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the polypeptide deformylase family.
 
    
 0.894
Tmar_1514
COGs: COG0208 Ribonucleotide reductase beta subunit; InterPro IPR000358; KEGG: aac:Aaci_0133 ribonucleotide reductase; PFAM: ribonucleotide reductase; SPTR: Ribonucleotide reductase; PFAM: Ribonucleotide reductase, small chain.
       0.773
Tmar_1515
Alcohol dehydrogenase GroES domain protein; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328: IPR013154: IPR013149; KEGG: bts:Btus_1061 alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase.
 
 
 0.665
Tmar_1880
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: sth:STH1117 putative oxidoreductase; PFAM: oxidoreductase domain protein; SPTR: Putative oxidoreductase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold.
  
  
 0.571
Tmar_1720
Iron-sulfur cluster binding protein; COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR017896: IPR004452: IPR017900: IPR018370: IPR 003741; KEGG: bts:Btus_2406 iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; SPTR: Iron-sulfur cluster binding protein; TIGRFAM: iron-sulfur cluster binding protein; PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein.
  
  
 0.496
Tmar_1080
AAA ATPase central domain protein; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593: IPR003959: IPR000641; KEGG: sth:STH1745 stage V sporulation protein K; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: Stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: stage V sporulation protein K.
    
  0.480
Tmar_1512
Protein of unknown function UCP033101; COGs: COG4377 membrane protein; InterPro IPR011397; KEGG: bur:Bcep18194_B0192 membrane protein; PFAM: protein of unknown function UCP033101; SPTR: Membrane protein; PFAM: Predicted membrane protein (DUF2324).
       0.447
Tmar_1626
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tro:trd_1049 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
  
 
 0.441
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.