STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psuGIndigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (410 aa)    
Predicted Functional Partners:
Tmar_1233
COGs: COG0213 Thymidine phosphorylase; InterPro IPR017872: IPR016192: IPR017459: IPR000312: IPR 013102: IPR002125: IPR018090: IPR006262; KEGG: gct:GC56T3_1191 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; CMP/dCMP deaminase zinc-binding; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; cytidine deaminase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helic [...]
 
 
  0.926
pyrR
Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.901
Tmar_1477
Amidohydrolase 3; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR013108; KEGG: tro:trd_1845 cytosine deaminase; PFAM: Amidohydrolase 3; SPTR: Cytosine deaminase; PFAM: Amidohydrolase family.
     
  0.900
Tmar_1526
Protein of unknown function DUF182; COGs: COG1975 Xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777; KEGG: dge:Dgeo_0385 hypothetical protein; PFAM: protein of unknown function DUF182; SPTR: Predicted oxidoreductase DUF182; PFAM: XdhC and CoxI family.
       0.773
Tmar_1527
COGs: COG0714 MoxR-like ATPase; InterPro IPR011704; KEGG: mrb:Mrub_1375 ATPase associated with various cellular activities AAA_5; PFAM: ATPase associated with various cellular activities AAA_5; SPTR: ATPase associated with various cellular activities AAA_5; PFAM: AAA domain (dynein-related subfamily).
       0.565
Tmar_0243
COGs: COG1957 Inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: rxy:Rxyl_1896 inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; SPTR: Inosine/uridine-preferring nucleoside hydrolase; PFAM: Inosine-uridine preferring nucleoside hydrolase.
 
    0.426
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.