STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Tmar_1698PTS system, glucose subfamily, IIA subunit; COGs: COG2190 Phosphotransferase system IIA components; InterPro IPR001127; KEGG: sth:STH348 PTS system enzyme IIABC component; PFAM: sugar-specific permease EIIA 1 domain; SPTR: PTS system enzyme IIABC component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component. (251 aa)    
Predicted Functional Partners:
Tmar_1696
PTS system N-acetylglucosamine-specific IIC component, Glc family; COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR013013: IPR003352; KEGG: tpd:Teth39_1823 PTS system, N-acetylglucosamine-specific IIBC subunit; PFAM: phosphotransferase system EIIC; SPTR: PTS system, N-acetylglucosamine-specific IIBC subunit; PFAM: Phosphotransferase system, EIIC; TC 4.A.1.1.7; TC 4.A.1.1.7.
 
 0.996
Tmar_2036
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.994
Tmar_2035
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698: IPR000032: IPR001020: IPR002114; KEGG: tte:TTE1820 phosphotransferase system, HPr-related proteins; PFAM: phosphoryl transfer system HPr; SPTR: Phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 0.984
Tmar_0444
Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857: IPR001347: IPR019490; KEGG: rmr:Rmar_1238 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); SPTR: Bifunctional phosphoglucose/phosphomannose isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase.
    
 0.923
Tmar_0507
ROK family protein; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tit:Thit_0081 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
  
 
 0.915
Tmar_1881
COGs: COG1109 Phosphomannomutase; InterPro IPR005841: IPR016066: IPR005844: IPR005845: IPR 005846: IPR005843; KEGG: sth:STH1118 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; PRIAM: Phosphomannomutase; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phospho [...]
     
 0.908
Tmar_0548
COGs: COG0380 Trehalose-6-phosphate synthase; InterPro IPR001830; KEGG: rmr:Rmar_0980 alpha,alpha-trehalose-phosphate synthase (UDP-forming); PFAM: glycosyl transferase family 20; PRIAM: Alpha,alpha-trehalose-phosphate synthase (UDP-forming); SPTR: Alpha,alpha-trehalose-phosphate synthase (UDP-forming); PFAM: Glycosyltransferase family 20; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming].
     
  0.900
Tmar_1695
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608: IPR004341; KEGG: drm:Dred_0333 transcriptional antiterminator, BglG; PFAM: PRD domain protein; CAT RNA-binding domain protein; SPTR: Transcriptional antiterminator, BglG; PFAM: CAT RNA binding domain; PRD domain.
 
 
 
 0.879
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
    
 
 0.873
Tmar_0383
Hypothetical protein; COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: aac:Aaci_2807 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Prolyl oligopeptidase family.
  
 
 
 0.845
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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