STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1851COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000276: IPR020845: IPR000873; KEGG: bts:Btus_1132 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme. (549 aa)    
Predicted Functional Partners:
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.793
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.699
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.696
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.692
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.689
Tmar_1852
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006089: IPR006091: IPR006090; KEGG: bts:Btus_1131 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain.
 
  
 0.688
Tmar_1404
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR000326: IPR004129; KEGG: dge:Dgeo_1506 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family; PAP2 superfamily.
   
 0.643
rpsQ
SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.639
Tmar_0897
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR013217: IPR006108: IPR001753; KEGG: sth:STH3012 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Methyltransferase type 12; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 
 0.636
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
    
 
 0.620
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.