STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmar_1925RNA methylase, NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR011023: IPR018314: IPR001678; KEGG: hha:Hhal_0056 Fmu (Sun) domain-containing protein; PFAM: Fmu (Sun) domain protein; PRIAM: tRNA (cytosine-5-)-methyltransferase; SPTR: Proliferating-cell nucleolar antigen; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase. (497 aa)    
Predicted Functional Partners:
def
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the polypeptide deformylase family.
 
  
 0.983
Tmar_0964
Ribosome biogenesis GTP-binding protein YlqF; COGs: COG1161 GTPase; InterPro IPR019991: IPR002917: IPR006073; KEGG: mta:Moth_0973 GTP-binding protein YlqF; PFAM: GTP-binding protein HSR1-related; SPTR: Ras superfamily GTP-binding protein YlqF; TIGRFAM: ribosome biogenesis GTP-binding protein YlqF; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YlqF.
   
 
 0.895
rplJ
LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.874
rplX
LSU ribosomal protein L24P; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
   
   0.844
rplW
LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
 
 0.843
rplV
LSU ribosomal protein L22P; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
   0.839
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
   0.838
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.837
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
   
   0.832
rplO
LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.831
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.