Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tmar_2007Hypothetical protein; KEGG: gem:GM21_1417 HAD-superfamily hydrolase, subfamily IA, variant 1; SPTR: P-type ATPase. (54 aa)    
Predicted Functional Partners:
Tmar_2006
Hypothetical protein; KEGG: gct:GC56T3_2009 haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase domain protein hydrolase.
       0.773
Tmar_2008
acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR005914: IPR017975: IPR020845: IPR000873; KEGG: bts:Btus_1007 acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase.
       0.411
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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