STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Tmar_2008acetoacetyl-CoA synthase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR005914: IPR017975: IPR020845: IPR000873; KEGG: bts:Btus_1007 acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; SPTR: Acetoacetyl-CoA synthase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase. (712 aa)    
Predicted Functional Partners:
Tmar_0897
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176: IPR013217: IPR006108: IPR001753; KEGG: sth:STH3012 3-hydroxyacyl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Methyltransferase type 12; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.962
Tmar_1049
hydroxymethylglutaryl-CoA lyase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: bge:BC1002_5140 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; PFAM: HMGL-like.
 
 0.944
Tmar_0274
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR020616: IPR020617: IPR002155: IPR020615: IPR 020610: IPR020613; KEGG: bts:Btus_3277 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; PRIAM: Acetyl-CoA C-acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
Tmar_2130
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006180: IPR006176: IPR006108; KEGG: msv:Mesil_2315 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; SPTR: 3-hydroxybutyryl-CoA dehydrogenase; PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 
 0.927
Tmar_2009
Protein of unknown function DUF1232; InterPro IPR010652; KEGG: chy:CHY_0109 hypothetical protein; PFAM: protein of unknown function DUF1232; SPTR: Conserved domain protein; PFAM: Protein of unknown function (DUF1232).
       0.542
Tmar_1299
COGs: COG0372 Citrate synthase; InterPro IPR019810: IPR002020: IPR011278; KEGG: bts:Btus_2368 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 
 0.516
Tmar_2000
COGs: COG0372 Citrate synthase; InterPro IPR002020: IPR019810; KEGG: aac:Aaci_0798 citrate synthase 3; PFAM: Citrate synthase; PRIAM: 2-methylcitrate synthase; SPTR: Citrate (Si)-synthase; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.516
Tmar_1398
COGs: COG2225 Malate synthase; InterPro IPR019830: IPR006252: IPR011076; KEGG: tro:trd_0495 malate synthase; PFAM: Malate synthase family protein; PRIAM: Malate synthase; SPTR: Malate synthase; TIGRFAM: malate synthase A; PFAM: Malate synthase; TIGRFAM: malate synthase A; Belongs to the malate synthase family.
   
 
 0.479
Tmar_1027
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterPro IPR001431: IPR011765: IPR007863; KEGG: mta:Moth_1059 peptidase M16-like; PFAM: peptidase M16 domain protein; SPTR: Peptidase M16-like; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
 
  
   0.462
Tmar_1851
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000276: IPR020845: IPR000873; KEGG: bts:Btus_1132 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
 
   0.462
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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