Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Tmar_2011COGs: COG0426 flavoprotein; KEGG: pth:PTH_0653 Zn-dependent hydrolases, including glyoxylases; SPTR: Zn-dependent hydrolases, including glyoxylases; PFAM: Metallo-beta-lactamase superfamily. (320 aa)    
Predicted Functional Partners:
Tmar_2010
Quinone oxidoreductase, YhdH/YhfP family; COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR014188: IPR013154: IPR013149; KEGG: gka:GK1429 hypothetical protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; SPTR: Hypothetical conserved protein; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: putative quinone oxidoreductase, YhdH/YhfP family.
       0.556
Tmar_1434
COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: ttr:Tter_0858 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.541
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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