STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (321 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.849
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.812
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.793
Tmar_2371
Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR013308: IPR020001; KEGG: pth:PTH_2919 preprotein translocase subunit YidC; PFAM: 60 kDa inner membrane insertion protein; SPTR: Preprotein translocase subunit YidC; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain.
  
  
 0.699
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.599
hemL
COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: sti:Sthe_1801 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase.
       0.557
Tmar_2370
COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: adg:Adeg_2148 single-stranded nucleic acid binding R3H domain protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Single-stranded nucleic acid binding R3H domain protein; PFAM: R3H domain.
  
    0.499
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
      0.487
Tmar_0261
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.478
Tmar_0526
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.478
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.