STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
satCOGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR020792: IPR002650; KEGG: sth:STH1143 sulfate adenylyltransferase; PFAM: ATP-sulfurylase; PRIAM: Sulfate adenylyltransferase; SPTR: Sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase; TIGRFAM: ATP sulphurylase; Belongs to the sulfate adenylyltransferase family. (495 aa)    
Predicted Functional Partners:
cysC
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the sulfate adenylyltransferase family.
 
 
0.976
Tmar_1022
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: sth:STH1524 exopolyphosphatase-related protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Exopolyphosphatase-related protein; PFAM: DHHA1 domain; DHH family.
     
  0.900
cysH-2
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
 
 0.891
Tmar_0381
COGs: COG0469 Pyruvate kinase; InterPro IPR015793: IPR001697: IPR015794: IPR008279; KEGG: adg:Adeg_0440 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
    0.819
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
  
 
 0.802
Tmar_1630
COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR006066: IPR005117: IPR006067; KEGG: rmr:Rmar_2355 ferredoxin--nitrite reductase; PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; SPTR: Ferredoxin--nitrite reductase; PFAM: Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain.
 
  
 0.749
Tmar_1629
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006367: IPR006366: IPR003043: IPR019478: IPR 000878; KEGG: yen:YE0761 siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Sirohaem synthase, dimerisation domain; SPTR: Sirohydrochlorin ferrochelatase; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Sirohaem synthase dimerisation region; Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase, N-terminal domain.
 
  
 0.592
Tmar_1260
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.575
Tmar_1626
COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: tro:trd_1049 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; PFAM: methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
 
  
 0.472
Tmar_1999
2-methylcitrate dehydratase; COGs: COG2079 Uncharacterized protein involved in propionate catabolism; InterPro IPR012705: IPR005656; KEGG: tro:trd_A0176 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family protein; PRIAM: 2-methylcitrate dehydratase; SPTR: 2-methylcitrate dehydratase; TIGRFAM: 2-methylcitrate dehydratase; PFAM: MmgE/PrpD family; TIGRFAM: 2-methylcitrate dehydratase.
 
 
    0.455
Your Current Organism:
Thermaerobacter marianensis
NCBI taxonomy Id: 644966
Other names: T. marianensis DSM 12885, Thermaerobacter marianensis 7p75a, Thermaerobacter marianensis ATCC 700841, Thermaerobacter marianensis DSM 12885, Thermaerobacter marianensis str. DSM 12885, Thermaerobacter marianensis strain DSM 12885
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